The new salvo follows the ANU's decision to divest shares in Sandfire and a number of other resource companies on environmental and ethical grounds.
It was made on the back of a report by the CAER, which Simich labelled "false, misleading and damaging"
"It's clear they did very little independently to verify the information gathered, based their conclusions only on summarised information and arrived at erroneous conclusions in the application of their own logic and methodology," Simich said.
The ANU decision has been criticised by a number of other parties, including Prime Minister Tony Abbott, who said the university had made a "stupid" decision and accused it of "unnecessary posturing"
Despite rising criticism, the move has found support in some parts of the community, with a number of prominent Australians and ethical investors supporting the action.
Simich said Sandfire supported the rights of investors to buy or sell on any grounds, but the CAER scorecard could unfairly skew public perception.
"What is at issue here and what is of great concern to us is the manner in which this profile was prepared by the CAER and then used as the basis to make misleading and inaccurate claims and arrive at erroneous conclusions, which have then been used as the basis for public statements," he said.
"Public statements should be based on facts, or at least opinions that are properly and fully informed."
Simich said researchers had not contacted Sandfire for a response prior to the report, and the ANU had its own responsibility to set the record straight and not mislead the community.
"We have further urged the ANU to publicly disclose the processes of due diligence they themselves are required to undertake under their own publicly available investment policy," he said.
The ANU and CAER were not available for comment.