WorkSafe Mines said it had received a report of a fatality at a mine in the Pilbara today but did not name the site.
Gold miner Capricorn Metals subsequently announced a "significant incident" had occurred at its Karlawinda site outside Newman this morning.
The incident resulted in the death of a contractor from MACA.
Mines safety inspectors are travelling to the site to investigate the incident. WA Police are also attending the scene.
Mining has been suspended.
"Everyone at Capricorn is shocked and saddened by the fatality at the Karlawinda mine site this morning," Capricorn executive chairman Mark Clark said.
"Our deepest thoughts and condolences go out to the MACA employee's family, friends and colleagues."
MACA is mobilising senior leaders to site and the company will provide direct support to the families and co-workers of those involved in the incident.
"Our thoughts are with the family, friends and workmates of our colleague," MACA CEO David Greig said.
"We will be providing support to our colleague's family and our teams as we all work through this tragic event."
The incident comes just two days after an underground contractor was killed at Gold Fields' St Ives gold mine in Kambalda on Tuesday.
"WorkSafe is unable to provide further details of either fatality at this time," it said.
WorkSafe WA commissioner Darren Kavanagh said any work-related death was a tragedy, and conveyed his sincere condolences to the worker's family, friends and co-workers.